Selecting which of your players to start in the right weeks will help you achieve success in the season. The Bruno Boys are here to help you with those crucial decisions, consider the tough matchups and warn you when your studs are facing defensive assignments that should temper your expectations. 

It’s playoff season now and we’re going to look to minimize the risk in our recommendations, while looking for big point potential, but still, staying in that range of the tougher decisions. Here are your Week 16 Fantasy Football Running Backs to Start.

Jaylen Samuels, Pittsburgh Steelers at New Orleans Saints

With James Conner out, Samuels will get the start and be able to build off of a strong Week 15 performance against the Patriots. He will have his work cut out for him though as the Saints have been brutal against the run, but the volume and opportunities will be there in a potential shootout in Week 16.