Who to start and who to sit? It’s the one question you need to answer right in order to do well in this crazy game of fantasy football. You won’t get it right every time but at Bruno Boys we help you work through those tougher decisions to make an informed and confident starting lineup.

Our Running Backs Starts and Sits look specifically at the line that separates RB2s and RB3s. Which ones are legit RB2 starts and which ones are better projected as a flex? We also consider PPR vs. standard, sleeper picks and streaming options too.

We will rarely cover studs unless it’s a sit recommendation based on matchup or we want to make note of a significant angle in the Quick Hits section at the end. Injuries happen too, which affects other players’ fantasy outlook. Lastly, bye weeks are a factor now.

Here are the Week 6 Fantasy Football Running Backs to Sit.

Miles Sanders, Philadelphia Eagles vs. Tampa Bay Buccaneers

You hate to see any lead back tumble down the ranks as quickly as Sanders has. He has been involved in both the run and pass plays but has failed to reach 8.0 fantasy points in four straight contests so it’s not easy to find reasons to start him, even as a weak flex. What’s worse is that Sanders is getting 75 percent of the snaps, while rookie back Kenneth Gainwell has just 25 percent. So it’s not like they’re sharing the field. It’s Sanders’ backfield.

Meanwhile the Bucs still have a good run defense. It’s not as good as it was last year and the back end of the defense has stretched holes for which some backs have been able to find holes. Guys like Myles Gaskin and Cordarrelle Patterson have had great success, while others like Damien Harris, Mike Davis and Zeke Elliott struggled. They’re only giving up 39.6 rushing yards per game to the position. Given the trend that Sanders is on, we’ll leave him on the bench until he shows us he can turn it around.